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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Frem1crf11
craniofacial 11
MGI:2671826
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Frem1crf11/Frem1crf11 involves: C57BL/6J MGI:3026630


Genotype
MGI:3026630
hm1
Allelic
Composition
Frem1crf11/Frem1crf11
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Frem1crf11 mutation (0 available); any Frem1 mutation (117 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• variable defects were noted

vision/eye
• high incidence of unilateral and bilateral cryptophthalmos

renal/urinary system
• unilateral renal agenesis in 6.9% of affected animals

digestive/alimentary system
• propensity to develop rectal prolapse in adulthood

respiratory system
• the cranial, medial, and caudal lobes of the right lung are partially or completely fused in 13/58 of affected mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory