growth/size/body
• at 12 weeks, male mice are lighter (34.1+/-0.6 g) compared to Mc4rm1Btlr homozygotes (38.8+/-1.0 g)
• at 20 weeks, male mice are lighter (43.0+/-0.7 g) compared to Mc4rm1Btlr homozygotes (48.8+/-0.3 g)
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• at 8 weeks, male mice are significantly heavier (28.2+/-0.6 g) than heterozygotes (26.5+/-0.4 g) and wild-type mice (24.9+/-0.4 g)
• at 14 weeks, female mice are heavier (26.9+/-1.3 g) than heterozygous (22.9+/-0.6 g) and wild-type mice (21.8+/-0.8 g)
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adipose tissue
• at 8 weeks, percent body fat in male mice is increased (14.3+/-1.5%) compared to in heterozygotes (9.6+/-0.8%) and wild-type mice (7.4+/-0.9%)
• at 20 weeks, percent body fat in male mice is increased (26.7+/-1.6%) compared to in heterozygotes (14.9+/-1.6%) and wild-type mice (10.0+/-2.6%)
• at 12 weeks, percent body fat in female mice is increased (15.6+/-1.5%) compared to in heterozygotes (10.6+/-1.0%) and wild-type mice (9.4+/-1.7%)
• at 20 weeks, percent body fat in female mice is increased (21.5+/-3.2%) compared to in heterozygotes (15.3+/-1.1%) and wild-type mice (9.0+/-1.9%)
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