Phenotypes associated with this allele

• Allele Symbol: l11Jus3
• Allele Name: lethal, Chr 11, Justice 3
• Allele ID: MGI:2671873
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	l11Jus3/l11Jus3	Not Specified	MGI:2673520

Genotype
MGI:2673520

hm1

• Allelic Composition: l11Jus3/l11Jus3
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:109155 )

• animals die between 5.5 and 8.5 dpc

embryo

abnormal developmental patterning ( J:85113 )

failure to gastrulate ( J:85113 )

abnormal embryonic tissue morphology ( J:109155 )

• homozygotes do not form embryonic cavities, suggesting a failure of axis organization and specification

abnormal egg cylinder morphology ( J:109155 )

abnormal visceral endoderm morphology ( J:85113 , J:109155 )

• abnormal visceral endoderm cells (J:85113)

• homozygotes lack differentiated visceral endoderm (J:109155)

• mutant visceral endoderm cells are morphologically abnormal (J:109155)

• visceral endoderm continues to grow with the egg cylinder, causing cells to appear lacy (J:109155)