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Allele Symbol Allele Name Allele ID |
Tg(Fabp1-cre)1Mmt transgene insertion 1, Makoto M Taketo MGI:2673819 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• die by 4-5 weeks of age of unknown causes
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• 200-700 intestinal polyps per mouse by 4 weeks of age
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• 200-700 intestinal polyps per mouse by 4 weeks of age
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• levels are slightly but significantly increased in males compared to wild-type at 9 weeks of age; these levels are still within normal range
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• 10-week old males fed a high sucrose (67%) diet (HSD) for 3 days have slightly decreased de novo lipogenesis compared to controls on the HSD, but levels are 3-fold higher than controls fed a normal diet
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• 10-week old males fed a high sucrose (67%) diet (HSD) for 3 days show ~70% decreased liver triglyceride levels than nontransgenic controls fed HSD
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• 10-week old males fed a high sucrose (67%) diet (HSD) for 3 days show ~70% decreased liver triglyceride levels than nontransgenic controls fed HSD
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/15/2024 MGI 6.24 |
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