About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Jak3tm1Jni
targeted mutation 1, James N Ihle
MGI:2675061
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Jak3tm1Jni/Jak3tm1Jni
Crlf2tm1Jni/Crlf2tm1Jni 		involves: 129P2/OlaHsd * C57BL/6 MGI:3039555


Genotype
MGI:3039555
cx1
Allelic
Composition		 Jak3tm1Jni/Jak3tm1Jni
Crlf2tm1Jni/Crlf2tm1Jni
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crlf2tm1Jni mutation (0 available); any Crlf2 mutation (21 available)
Jak3tm1Jni mutation (0 available); any Jak3 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:89031 )
• loss of the residual splenic B220+ lymphoctyte population that persists in Jak3tm1Jni homozygotes

immune system
decreased B cell number ( J:89031 )
• loss of the residual splenic B220+ lymphoctyte population that persists in Jak3tm1Jni homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory