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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Jak3tm1Jni
targeted mutation 1, James N Ihle
MGI:2675061
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Jak3tm1Jni/Jak3tm1Jni
Crlf2tm1Jni/Crlf2tm1Jni 		involves: 129P2/OlaHsd * C57BL/6 MGI:3039555


Genotype
MGI:3039555
cx1
Allelic
Composition		 Jak3tm1Jni/Jak3tm1Jni
Crlf2tm1Jni/Crlf2tm1Jni
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crlf2tm1Jni mutation (0 available); any Crlf2 mutation (21 available)
Jak3tm1Jni mutation (0 available); any Jak3 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:89031 )
• loss of the residual splenic B220+ lymphoctyte population that persists in Jak3tm1Jni homozygotes

immune system
decreased B cell number ( J:89031 )
• loss of the residual splenic B220+ lymphoctyte population that persists in Jak3tm1Jni homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory