Phenotypes associated with this allele

• Allele Symbol: Rr142^tm1.1Rud
• Allele Name: targeted mutation 1.1, Frank H Ruddle
• Allele ID: MGI:2675412
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr142^tm1.1Rud/Rr142^tm1.1Rud	involves: 129S1/Sv * C57BL/6	MGI:2675417

Genotype
MGI:2675417

hm1

• Allelic Composition: Rr142^tm1.1Rud/Rr142^tm1.1Rud
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

thoracic vertebral transformation ( J:85471 )

• low penetrance of anterior transformation of the 7th thoracic vertebrae (T7) to the 6th thoracic vertebrae (T6)

• 90% penentrance of anterior transformation of T8 to T7

cervical vertebral transformation ( J:85471 )

• low penetrance of posterior transformation of the 7th cervical vertebrae (C7) to the first thoracic vertebrae (T1)

lumbar vertebral transformation ( J:85471 )

• low penetrance of anterior transformation of the first lumbar vertebrae (L1) to the 13th thoracic vertebrae (T13)

behavior/neurological

limb grasping ( J:85471 )

• about 30% of mutants show abnormal contraction and clasping reflex of the fore- and hindlimbs upon suspension