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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nr2c1tm1Chc
targeted mutation 1, Chawnshang Chang
MGI:2675740
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nr2c1tm1Chc/Nr2c1tm1Chc involves: 129S5/SvEvBrd MGI:3711145
hm2
 		Nr2c1tm1Chc/Nr2c1tm1Chc involves: 129S5/SvEvBrd * C57BL/6 MGI:2675744


Genotype
MGI:3711145
hm1
Allelic
Composition		 Nr2c1tm1Chc/Nr2c1tm1Chc
Genetic
Background		 involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr2c1tm1Chc mutation (0 available); any Nr2c1 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal hemoglobin ( J:121628 )
• at E13.5, betaH1 globin silencing is significantly delayed
• however, epsilon-y and adult beta-globin genes are unaffected




Genotype
MGI:2675744
hm2
Allelic
Composition		 Nr2c1tm1Chc/Nr2c1tm1Chc
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr2c1tm1Chc mutation (0 available); any Nr2c1 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:77023 )
• viable and fertile; homozygous mice do not exhibit any defects in testis development or in spermatogenesis; no gross defects were detected in the central nervous system and normal motor neuron cell numbers were noted




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory