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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fbxo32tm1Glas
targeted mutation 1, David J Glass
MGI:2676047
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fbxo32tm1Glas/Fbxo32tm1Glas involves: 129S1/Sv MGI:2681612


Genotype
MGI:2681612
hm1
Allelic
Composition		 Fbxo32tm1Glas/Fbxo32tm1Glas
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo32tm1Glas mutation (0 available); any Fbxo32 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
decreased susceptibility to induced muscular atrophy ( J:77660 )
• upon sciatic nerve denervation, mice exhibit muscle atrophy at a reduced level compared to wild-type
• 56% muscle sparing was noted at 14 days post-denervation compared to wild-type mice
• mean muscle fiber size and fiber size variability remained similar to undenervated controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory