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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Igf2tm1Kel
targeted mutation 1, Gavin Derek Kelsey
MGI:2677154
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Igf2tm1Kel/Igf2+
Phlda2tm1Bty/Phlda2+ 		involves: 129/Sv * C57BL/6 MGI:3042598
cx2
 		Igf2tm1Kel/Igf2+
Phlda2tm2Bty/Phlda2+ 		involves: 129/Sv * C57BL/6 MGI:3042599


Genotype
MGI:3042598
cx1
Allelic
Composition		 Igf2tm1Kel/Igf2+
Phlda2tm1Bty/Phlda2+
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igf2tm1Kel mutation (0 available); any Igf2 mutation (28 available)
Phlda2tm1Bty mutation (0 available); any Phlda2 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
increased spongiotrophoblast size ( J:76871 )
• spongiotrophoblast is expanded relative to the trophoblast labyrinth
decreased placenta weight ( J:76871 )
• placental weight is decreased relative to controls but greater than in mice homozygous only forIgf2tm1Kel

growth/size/body
decreased fetal weight ( J:76871 )
• fetal weight was decreased compared to controls




Genotype
MGI:3042599
cx2
Allelic
Composition		 Igf2tm1Kel/Igf2+
Phlda2tm2Bty/Phlda2+
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igf2tm1Kel mutation (0 available); any Igf2 mutation (28 available)
Phlda2tm2Bty mutation (0 available); any Phlda2 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
increased spongiotrophoblast size ( J:76871 )
• spongiotrophoblast is expanded relative to the trophoblast labyrinth
decreased placenta weight ( J:76871 )
• placental weight is decreased relative to controls but greater than in mice homozygous only forIgf2tm1Kel-p

growth/size/body
decreased fetal weight ( J:76871 )
• fetal weight was decreased compared to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory