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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ephb1tm2Cmn
targeted mutation 2, Carol A Mason
MGI:2677312
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ephb1tm1Cmn/Ephb1tm2Cmn involves: 129S1/Sv * 129X1/SvJ * CD-1 MGI:2677322


Genotype
MGI:2677322
ht1
Allelic
Composition		 Ephb1tm1Cmn/Ephb1tm2Cmn
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ephb1tm1Cmn mutation (1 available); any Ephb1 mutation (43 available)
Ephb1tm2Cmn mutation (0 available); any Ephb1 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal eye morphology ( J:85573 )
• express beta-gal in cells normally expressing Ephb1
abnormal optic nerve innervation ( J:85573 )
• embryos demonstrate misprojection of axons contralaterally

nervous system
abnormal optic nerve innervation ( J:85573 )
• embryos demonstrate misprojection of axons contralaterally




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory