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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gabrb2tm1.1Kwa
targeted mutation 1.1, Keith A Wafford
MGI:2677669
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gabrb2tm1.1Kwa/Gabrb2tm1.1Kwa involves: 129S7/SvEvBrd * C57BL/6 MGI:2677683


Genotype
MGI:2677683
hm1
Allelic
Composition
Gabrb2tm1.1Kwa/Gabrb2tm1.1Kwa
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gabrb2tm1.1Kwa mutation (0 available); any Gabrb2 mutation (44 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• shorter anaesthetic effects of etomidate administration as measured by loss of righting reflex and loss of pedal withdrawl reflex
• recovery as measured in a rotarod test also more rapid
• low doses of etomidate i.p. did not affect exploratory behavior





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory