About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cplx2tm1Tyag
targeted mutation 1, Takeshi Yagi
MGI:2680035
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cplx2tm1Tyag/Cplx2tm1Tyag B6.Cg-Cplx2tm1Tyag MGI:3719642
hm2
 		Cplx2tm1Tyag/Cplx2tm1Tyag involves: C57BL/6 * CBA MGI:3719586


Genotype
MGI:3719642
hm1
Allelic
Composition		 Cplx2tm1Tyag/Cplx2tm1Tyag
Genetic
Background		 B6.Cg-Cplx2tm1Tyag
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cplx2tm1Tyag mutation (0 available); any Cplx2 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term potentiation ( J:106335 )
• long term potential does not increase as in wild-type mice as the level of tetanic stimulation is increased and is less than wild-type at 100 Hz




Genotype
MGI:3719586
hm2
Allelic
Composition		 Cplx2tm1Tyag/Cplx2tm1Tyag
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cplx2tm1Tyag mutation (0 available); any Cplx2 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term potentiation ( J:57368 )
• tetanic stimulated long term potentials in Sch/Com-CA1 and mossy-fiber-CA3 circuits are reduced




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory