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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prkcetm1Ltg
targeted mutation 1, Michael Leitges
MGI:2680163
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prkcetm1Ltg/Prkcetm1Ltg involves: 129P2/OlaHsd * FVB/N MGI:2680170


Genotype
MGI:2680170
hm1
Allelic
Composition		 Prkcetm1Ltg/Prkcetm1Ltg
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkcetm1Ltg mutation (0 available); any Prkce mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased tumor necrosis factor secretion ( J:86056 )
• significantly reduced production of TNF-alpha by keratinocytes after stimulation with ethanol or TPA




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory