Phenotypes associated with this allele

• Allele Symbol: Gnaq^Mhdadsk1
• Allele Name: Martin Hrabe de Angelis dark skin 1
• Allele ID: MGI:2681766
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gnaq^Mhdadsk1/Gnaq^Mhdadsk1	involves: C3HeB/FeJ * C57BL/6J	MGI:3530608
ht2	Gnaq^Mhdadsk1/Gnaq^+	C3HeB/FeJ-Gnaq^Mhdadsk1/Ieg	MGI:2681769

Genotype
MGI:3530608

hm1

• Allelic Composition: Gnaq^Mhdadsk1/Gnaq^Mhdadsk1
• Genetic Background: involves: C3HeB/FeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:86685 )

• black pigmentation of the tail

• more severe in homozygous than heterozygous animals

hearing/vestibular/ear

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

limbs/digits/tail

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:86685 )

• black pigmentation of the tail

• more severe in homozygous than heterozygous animals

craniofacial

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

integument

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:86685 )

• black pigmentation of the tail

• more severe in homozygous than heterozygous animals

growth/size/body

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

Genotype
MGI:2681769

ht2

• Allelic Composition: Gnaq^Mhdadsk1/Gnaq⁺
• Genetic Background: C3HeB/FeJ-Gnaq^Mhdadsk1/Ieg

pigmentation

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

abnormal skin pigmentation ( J:81301 )

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:86685 )

• black pigmentation of the tail

• more severe in homozygous than heterozygous animals

hearing/vestibular/ear

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

limbs/digits/tail

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:86685 )

• black pigmentation of the tail

• more severe in homozygous than heterozygous animals

craniofacial

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

integument

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

abnormal skin pigmentation ( J:81301 )

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:86685 )

• black pigmentation of the tail

• more severe in homozygous than heterozygous animals

growth/size/body

increased ear pigmentation ( J:86685 )

• black pigmentation of the ears

• more severe in homozygous than heterozygous animals