Phenotypes associated with this allele

• Allele Symbol: Gnaq^Mhdadsk10
• Allele Name: Martin Hrabe de Angelis dark skin 10
• Allele ID: MGI:2681784
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gnaq^Mhdadsk10/Gnaq^Mhdadsk10	C3HeB/FeJ-Gnaq^Dsk10	MGI:3576330
ht2	Gnaq^Mhdadsk10/Gnaq^+	C3HeB/FeJ-Gnaq^Dsk10	MGI:2681785

Genotype
MGI:3576330

hm1

• Allelic Composition: Gnaq^Mhdadsk10/Gnaq^Mhdadsk10
• Genetic Background: C3HeB/FeJ-Gnaq^Dsk10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

hyperpigmentation ( J:81301 )

• excess pigmentation is first seen at P3 increases through weaning then fades with age

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

hearing/vestibular/ear

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

limbs/digits/tail

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

craniofacial

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

integument

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

growth/size/body

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

Genotype
MGI:2681785

ht2

• Allelic Composition: Gnaq^Mhdadsk10/Gnaq⁺
• Genetic Background: C3HeB/FeJ-Gnaq^Dsk10

pigmentation

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

hyperpigmentation ( J:81301 )

• excess pigmentation is first seen at P3 increases through weaning then fades with age

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

hearing/vestibular/ear

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

limbs/digits/tail

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

craniofacial

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

integument

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals

darkened coat color ( J:81301 )

• slight darkening of the hair

• more severe in homozygous than heterozygous animals

increased foot pad pigmentation ( J:81301 )

• excess pigment in a uniform and slanted stripe prominent over the volar pad at the base of the first digit; bluish-gray in color

• more severe in homozygous than heterozygous animals

increased tail pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the tail

• more severe in homozygous than heterozygous animals

growth/size/body

increased ear pigmentation ( J:81301 )

• extremely dark pigmentation in dermis of the ears

• more severe in homozygous than heterozygous animals