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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hmmrtm1Baa
targeted mutation 1, Benjamin A Alman
MGI:2682898
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hmmrtm1Baa/Hmmrtm1Baa involves: 129P2/OlaHsd * C57BL/6 MGI:2682908
cx2
 		Apctm1Rak/Apc+
Hmmrtm1Baa/Hmmrtm1Baa 		involves: 129P2/OlaHsd * C57BL/6 MGI:2682909


Genotype
MGI:2682908
hm1
Allelic
Composition		 Hmmrtm1Baa/Hmmrtm1Baa
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmmrtm1Baa mutation (0 available); any Hmmr mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reduced fertility ( J:86065 )
• homozygous matings resulted in significantly fewer viable litters compared to either heterozygous or wild-type matings




Genotype
MGI:2682909
cx2
Allelic
Composition		 Apctm1Rak/Apc+
Hmmrtm1Baa/Hmmrtm1Baa
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Rak mutation (1 available); any Apc mutation (158 available)
Hmmrtm1Baa mutation (0 available); any Hmmr mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased tumor incidence ( J:86065 )
• decreased number of aggressive fibromatosis tumors formed relative to Apctm1Rak heterozygotes
• the number of gastrointestinal polyps was not altered relative to Apctm1Rak heterozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory