Phenotypes associated with this allele

• Allele Symbol: hlb52
• Allele Name: heart, lung and blood, 52
• Allele ID: MGI:2683068
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	hlb52/hlb52	C57BL/6J-hlb52/J	MGI:3795970
ot2	hlb52/?	C57BL/6J-hlb52/J	MGI:2683070

Genotype
MGI:3795970

hm1

• Allelic Composition: hlb52/hlb52
• Genetic Background: C57BL/6J-hlb52/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased percent body fat/body weight ( J:82961 )

• percent body fat of 12 week old females on a high fat, high cholesterol diet is 28.3%

growth/size/body

increased susceptibility to diet-induced obesity ( J:82961 )

• body weight of 12 week old females on a high fat, high cholesterol diet is 21.5 grams, which is comparable to C57BL/6J controls on the same diet

homeostasis/metabolism

increased susceptibility to diet-induced obesity ( J:82961 )

• body weight of 12 week old females on a high fat, high cholesterol diet is 21.5 grams, which is comparable to C57BL/6J controls on the same diet

Genotype
MGI:2683070

ot2

• Allelic Composition: hlb52/?
• Genetic Background: C57BL/6J-hlb52/J

adipose tissue

increased percent body fat/body weight ( J:82961 )

• at age 12 weeks, percent body fat = 28.3 after consuming an atherogenic diet for 4 weeks

growth/size/body

increased body weight ( J:82961 )

• at age 12 weeks, body weight = 21.5 grams after consuming an atherogenic diet for 4 weeks

obese ( J:82961 )

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:82961 )

N • insulin = 0.659 pg/ml, leptin = 13.29 ng/ml