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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdk5r1tm1Ivi
targeted mutation 1, Inez Vincent
MGI:2683302
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdk5r1tm1Ivi/Cdk5r1tm1Ivi B6.Cg-Cdk5r1tm1Ivi MGI:2683312


Genotype
MGI:2683312
hm1
Allelic
Composition		 Cdk5r1tm1Ivi/Cdk5r1tm1Ivi
Genetic
Background		 B6.Cg-Cdk5r1tm1Ivi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk5r1tm1Ivi mutation (0 available); any Cdk5r1 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal stratification in cerebral cortex ( J:86345 )
• lack normal cortical lamination
delaminated Purkinje cell layer ( J:86345 )
• Purkinje neurons are located ectopically in the granule cell layer sometimes forming a multilayered structure
ectopic cerebellar granule cells ( J:86345 )
• some granule cells are located in the molecular layer




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory