Analysis Tools
mortality/aging
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• mice die shortly after birth
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cardiovascular system
limbs/digits/tail
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• gross limb dysmorphology due to patterning defects
• in the zeugopod, in both forelimb and hindlimb of mutant fetuses, the posterior skeletal element is transformed into a replica of the anterior element
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skeleton
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• abnormalities of limb development began at the level of the scapula
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• often a large hole was present at the scapular spine
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vision/eye
nervous system
