Phenotypes associated with this allele

• Allele Symbol: Blm^tm3Ches
• Allele Name: targeted mutation 3, Nicholas Chester
• Allele ID: MGI:2683764
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Blm^tm3Ches/Blm^tm3Ches	involves: 129S6/SvEvTac * NIH Black Swiss	MGI:2683776

Genotype
MGI:2683776

hm1

• Allelic Composition: Blm^tm3Ches/Blm^tm3Ches
• Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:86827 )

• no homozygotes born from crosses of heterozygous parents

• embryonic death occurred before E13.5

embryo

decreased embryo size ( J:86827 )

growth/size/body

decreased embryo size ( J:86827 )

postnatal growth retardation ( J:86827 )

hematopoietic system

abnormal erythrocyte morphology ( J:86827 )

• multinucleated red blood cells

• reduced numbers of red blood cells

• pale appearance of embryos

anisopoikilocytosis ( J:86827 )

• red blood cells of abnormal shapes and size

• red blood cells were enlarged

integument

pallor ( J:86827 )