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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pde7aGt(Betageo-puro)1Yang
gene trap 1, Guchen Yang
MGI:2684009
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pde7aGt(Betageo-puro)1Yang/Pde7aGt(Betageo-puro)1Yang involves: 129P2/OlaHsd * C57BL/6 MGI:2684015


Genotype
MGI:2684015
hm1
Allelic
Composition		 Pde7aGt(Betageo-puro)1Yang/Pde7aGt(Betageo-puro)1Yang
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde7aGt(Betageo-puro)1Yang mutation (0 available); any Pde7a mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal humoral immune response ( J:86923 )
• elevated antibody response to a T cell-dependent antigen (keyhole limpet hemocyanin)
• T cells were functional with respect to proliferative response and cytokine production in vitro and in T cell-dependent antibody response in vivo




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory