About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pde7aGt(Betageo-puro)1Yang
gene trap 1, Guchen Yang
MGI:2684009
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pde7aGt(Betageo-puro)1Yang/Pde7aGt(Betageo-puro)1Yang involves: 129P2/OlaHsd * C57BL/6 MGI:2684015


Genotype
MGI:2684015
hm1
Allelic
Composition		 Pde7aGt(Betageo-puro)1Yang/Pde7aGt(Betageo-puro)1Yang
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde7aGt(Betageo-puro)1Yang mutation (0 available); any Pde7a mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal humoral immune response ( J:86923 )
• elevated antibody response to a T cell-dependent antigen (keyhole limpet hemocyanin)
• T cells were functional with respect to proliferative response and cytokine production in vitro and in T cell-dependent antibody response in vivo




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory