Phenotypes associated with this allele

• Allele Symbol: Cacnb4^lh-3J
• Allele Name: lethargic 3 Jackson
• Allele ID: MGI:2684216
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cacnb4^lh-3J/Cacnb4^lh-3J	C3HeB/FeJ-Cacnb4^lh-3J/GrsrJ	MGI:3033221

Genotype
MGI:3033221

hm1

• Allelic Composition: Cacnb4^lh-3J/Cacnb4^lh-3J
• Genetic Background: C3HeB/FeJ-Cacnb4^lh-3J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

lethargy ( J:88414 )

• some lh-3J mice also have a stargazing phenotype, where their heads frequently point upwards, but seizures have not been reported

abnormal head movements ( J:88414 )

abnormal locomotor behavior ( J:88414 )

abnormal gait ( J:88414 )

• mice exhibit a behavior characteristic of other alleles of lethargic, with a wobbly gait resembling an unsteady wide legged shuffle

• this phenotype is recognizable by 14 days of age

growth/size/body

decreased body size ( J:88414 )

• homozygotes are smaller than their littermates but live a nornal lifespan