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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fabp1tm1Ddsn
targeted mutation 1, Nicholas O Davidson
MGI:2687013
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fabp1tm1Ddsn/Fabp1tm1Ddsn involves: 129X1/SvJ * C57BL/6 MGI:2687023


Genotype
MGI:2687023
hm1
Allelic
Composition		 Fabp1tm1Ddsn/Fabp1tm1Ddsn
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fabp1tm1Ddsn mutation (0 available); any Fabp1 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating insulin level ( J:87278 )
• serum insulin levels were significantly reduced in fed homozygous males
abnormal lipid homeostasis ( J:87278 )
• except as noted, lipid levels and lipid binding protein levels remained normal
abnormal lipid level ( J:87278 )
• less neutral lipid in livers of fasting animals
• ketone body production increases less than in wild-type mice
decreased liver triglyceride level ( J:87278 )
• approximately 4 fold reduction in liver triglycerides in fasting animals

liver/biliary system
decreased liver triglyceride level ( J:87278 )
• approximately 4 fold reduction in liver triglycerides in fasting animals




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory