behavior/neurological
limb grasping
(
J:87289
)
• mice grasp their hind limbs when picked up by the tail
|
• mutants show a reduced ability to hold onto an edge
• forelimbs show normal strength
|
• unlike the less severe rb mutant, rb-2J mutant mice lean frequently to either side
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• this allele causes leaning, not reported for other alleles
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abnormal gait
(
J:87289
)
• mutant mice can be identified by 2.5-3 weeks of age by a constant hopping gait of the hindlimbs
• the forelimbs may show a hopping gait or move normally
|
• females are poor at nurturing their young
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endocrine/exocrine glands
cryptorchism
(
J:87289
)
• males sometimes have undescended testes and fail to breed
|
reproductive system
cryptorchism
(
J:87289
)
• males sometimes have undescended testes and fail to breed
|
• females produce small litters
|
• due to undescended testes
|