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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Epha4rb-2J
rabbit 2 Jackson
MGI:2687029
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Epha4rb-2J/Epha4rb-2J C57BL/6J-Epha4rb-2J/GrsrJ MGI:2687080


Genotype
MGI:2687080
hm1
Allelic
Composition
Epha4rb-2J/Epha4rb-2J
Genetic
Background
C57BL/6J-Epha4rb-2J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epha4rb-2J mutation (1 available); any Epha4 mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice grasp their hind limbs when picked up by the tail
• mutants show a reduced ability to hold onto an edge
• forelimbs show normal strength
• unlike the less severe rb mutant, rb-2J mutant mice lean frequently to either side
• this allele causes leaning, not reported for other alleles
• mutant mice can be identified by 2.5-3 weeks of age by a constant hopping gait of the hindlimbs
• the forelimbs may show a hopping gait or move normally
• females are poor at nurturing their young

endocrine/exocrine glands
• males sometimes have undescended testes and fail to breed

reproductive system
• males sometimes have undescended testes and fail to breed
• females produce small litters
• due to undescended testes





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory