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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Efnb2tm4Kln
targeted mutation 4, Rudiger Klein
MGI:3026687
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Efnb2tm4Kln/Efnb2tm4Kln
Tg(Camk2a-cre)159Kln/0
involves: 129P2/OlaHsd * C57BL/6 MGI:3026783
cn2
Efnb2tm4Kln/Efnb2tm4Kln
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 MGI:3026784


Genotype
MGI:3026783
cn1
Allelic
Composition
Efnb2tm4Kln/Efnb2tm4Kln
Tg(Camk2a-cre)159Kln/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb2tm4Kln mutation (0 available); any Efnb2 mutation (29 available)
Tg(Camk2a-cre)159Kln mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice showed no overt behavioral abnormalities

nervous system
N
• normal hippocampal architecture
• reduced early LTP but no significant defects of basal synaptic transmission parameters or NMDA receptor component




Genotype
MGI:3026784
cn2
Allelic
Composition
Efnb2tm4Kln/Efnb2tm4Kln
Tg(Nes-cre)1Kln/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb2tm4Kln mutation (0 available); any Efnb2 mutation (29 available)
Tg(Nes-cre)1Kln mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• normal hippocampal architecture
• reduced long term depression





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory