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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cntnap1tm1Pele
targeted mutation 1, Elior Peles
MGI:3026869
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cntnap1tm1Pele/Cntnap1tm1Pele involves: ICR MGI:4840028
hm2
 		Cntnap1tm1Pele/Cntnap1tm1Pele Not Specified MGI:3027010
cx3
 		Cntnap1tm1Pele/Cntnap1tm1Pele
Nrcamtm1Gmt/Nrcamtm1Gmt 		involves: 129P2/OlaHsd * ICR MGI:4840027
cx4
 		Cntnap1tm1Pele/Cntnap1tm1Pele
Gldntm1Pele/Gldntm1Pele 		involves: ICR MGI:4840026


Genotype
MGI:4840028
hm1
Allelic
Composition		 Cntnap1tm1Pele/Cntnap1tm1Pele
Genetic
Background		 involves: ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntnap1tm1Pele mutation (0 available); any Cntnap1 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
ataxia ( J:166099 )
• mild

nervous system




Genotype
MGI:3027010
hm2
Allelic
Composition		 Cntnap1tm1Pele/Cntnap1tm1Pele
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntnap1tm1Pele mutation (0 available); any Cntnap1 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon morphology ( J:87070 )
• paranodal abnormalities due to affected contactin processing




Genotype
MGI:4840027
cx3
Allelic
Composition		 Cntnap1tm1Pele/Cntnap1tm1Pele
Nrcamtm1Gmt/Nrcamtm1Gmt
Genetic
Background		 involves: 129P2/OlaHsd * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntnap1tm1Pele mutation (0 available); any Cntnap1 mutation (56 available)
Nrcamtm1Gmt mutation (1 available); any Nrcam mutation (87 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

nervous system
abnormal axon morphology ( J:166099 )
• nodes and heminodes fail to form unlike in wild-type mice
• nodal length is increased compared to in wild-type mice

behavior/neurological
ataxia ( J:166099 )
• strong congenital at P4




Genotype
MGI:4840026
cx4
Allelic
Composition		 Cntnap1tm1Pele/Cntnap1tm1Pele
Gldntm1Pele/Gldntm1Pele
Genetic
Background		 involves: ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntnap1tm1Pele mutation (0 available); any Cntnap1 mutation (56 available)
Gldntm1Pele mutation (0 available); any Gldn mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

nervous system
abnormal axon morphology ( J:166099 )
• nodes and heminodes fail to form unlike in wild-type mice
• nodal length is increased compared to in wild-type mice

behavior/neurological
ataxia ( J:166099 )
• strong congenital at P5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory