About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		C5ar1tm1Raw
targeted mutation 1, Rick A Wetsel
MGI:3028524
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		C5ar1tm1Raw/C5ar1tm1Raw B6.Cg-C5ar1tm1Raw MGI:3811741
hm2
 		C5ar1tm1Raw/C5ar1tm1Raw involves: C57BL/6J MGI:3028526


Genotype
MGI:3811741
hm1
Allelic
Composition		 C5ar1tm1Raw/C5ar1tm1Raw
Genetic
Background		 B6.Cg-C5ar1tm1Raw
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
C5ar1tm1Raw mutation (0 available); any C5ar1 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:139786 )
N
• mice are normally susceptible to experimentally induced autoimmune myasthenia gravis and normal antibody and lymphocyte proliferation in response
increased spleen germinal center number ( J:139786 )
• in response to induction of experimentally induced autoimmune myasthenia gravis

hematopoietic system
increased spleen germinal center number ( J:139786 )
• in response to induction of experimentally induced autoimmune myasthenia gravis




Genotype
MGI:3028526
hm2
Allelic
Composition		 C5ar1tm1Raw/C5ar1tm1Raw
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
C5ar1tm1Raw mutation (0 available); any C5ar1 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:86845 )
N
• antiphospholipid antibodies did not cause an increase in fetal resorption in homozygotes as they did in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory