About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Elk1tm1Nor
targeted mutation 1, Alfred Nordheim
MGI:3028871
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Elk1tm1Nor/Y
Elk4tm1Rtr/Elk4tm1Rtr
involves: 129P2/OlaHsd MGI:5790493
cx2
Elk1tm1Nor/Elk1tm1Nor
Elk4tm1Rtr/Elk4tm1Rtr
involves: 129P2/OlaHsd MGI:5790494
ot3
Elk1tm1Nor/Y involves: 129P2/OlaHsd * C57BL/6N MGI:3028877


Genotype
MGI:5790493
cx1
Allelic
Composition
Elk1tm1Nor/Y
Elk4tm1Rtr/Elk4tm1Rtr
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elk1tm1Nor mutation (0 available); any Elk1 mutation (8 available)
Elk4tm1Rtr mutation (0 available); any Elk4 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
N
• adult mice show no apparent changes in retinal arterial shapes, lengths and widths nor in retinal layering and layer thickness relative to wild-type controls
• no retinal neovascularization is observed




Genotype
MGI:5790494
cx2
Allelic
Composition
Elk1tm1Nor/Elk1tm1Nor
Elk4tm1Rtr/Elk4tm1Rtr
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elk1tm1Nor mutation (0 available); any Elk1 mutation (8 available)
Elk4tm1Rtr mutation (0 available); any Elk4 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
N
• adult mice show no apparent changes in retinal arterial shapes, lengths and widths nor in retinal layering and layer thickness relative to wild-type controls
• no retinal neovascularization is observed




Genotype
MGI:3028877
ot3
Allelic
Composition
Elk1tm1Nor/Y
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elk1tm1Nor mutation (0 available); any Elk1 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• normal T-cell maturation
• normal response to coxsackievirus

reproductive system
• male sterility due probably to aberrant Tk expression in testes

nervous system
N
• essentially normal although c-fos expression in the cortex and hippocampal CA1 after kainic acid injection was impaired

cellular





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory