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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tb2r1DBA/2J
DBA/2J
MGI:3029245
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tb2r1DBA/2J/Tb2r1DBA/2J B6.D2-(D4Mit37-tel) MGI:3821867
ot2
 		Tb2r1DBA/2J/? involves: C57BL/6J * DBA/2J MGI:3029288


Genotype
MGI:3821867
hm1
Allelic
Composition		 Tb2r1DBA/2J/Tb2r1DBA/2J
Genetic
Background		 B6.D2-(D4Mit37-tel)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal definitive hematopoiesis ( J:140749 )
• decreased Lin(-)Sca1(++)c-kit(+) (LSK) cell frequency
• decreased LSK cell responsiveness to low concentrations of TFG-beta2
• decreased cycling of hemotopoietic stem and progenitor cell (HSPC) compartment




Genotype
MGI:3029288
ot2
Allelic
Composition		 Tb2r1DBA/2J/?
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal definitive hematopoiesis ( J:87437 )
• increased number of LSK primitive progenitor cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory