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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		HnrnpcGt(U3His)4A4Rul
gene trap 4A4, H Earl Ruley
MGI:3029723
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		HnrnpcGt(U3His)4A4Rul/HnrnpcGt(U3His)4A4Rul involves: 129S2/SvPas * C57BL/6 MGI:3029725


Genotype
MGI:3029725
hm1
Allelic
Composition		 HnrnpcGt(U3His)4A4Rul/HnrnpcGt(U3His)4A4Rul
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
HnrnpcGt(U3His)4A4Rul mutation (0 available); any Hnrnpc mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:62141 )
• homozygous embryos fail to develop beyond the egg cylinder stage and are resorbed between E6.5 to E10.5

embryo
failure to gastrulate ( J:62141 )
• embryos do not exhibit any gastrulation movements
embryonic growth arrest ( J:62141 )
• embryos develop until the egg cylinder stage, then do not develop further




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory