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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Idd6NOD
NOD
MGI:3036667
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Idd6NOD/Idd6NOD B6.NOD-Idd6 MGI:3043983
hm2
 		Idd6NOD/Idd6NOD involves: C57BL/6 * NOD MGI:3037124
ht3
 		Idd6C57BL/6/Idd6NOD involves: C57BL/6 * NOD MGI:3037125


Genotype
MGI:3043983
hm1
Allelic
Composition		 Idd6NOD/Idd6NOD
Genetic
Background		 B6.NOD-Idd6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd6NOD mutation (2 available); any Idd6 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal NK cell physiology ( J:85823 )
• defective IFN-gamma response in NK cells when challenged with antigen

hematopoietic system
abnormal NK cell physiology ( J:85823 )
• defective IFN-gamma response in NK cells when challenged with antigen




Genotype
MGI:3037124
hm2
Allelic
Composition		 Idd6NOD/Idd6NOD
Genetic
Background		 involves: C57BL/6 * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd6NOD mutation (2 available); any Idd6 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system

cellular
decreased apoptosis ( J:84296 )
• resistance to apoptosis in immatures thymocytes following dexamethazone treatment

hematopoietic system




Genotype
MGI:3037125
ht3
Allelic
Composition		 Idd6C57BL/6/Idd6NOD
Genetic
Background		 involves: C57BL/6 * NOD
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd6C57BL/6 mutation (1 available); any Idd6 mutation (3 available)
Idd6NOD mutation (2 available); any Idd6 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system

cellular
decreased apoptosis ( J:84296 )
• resistance to apoptosis in immature thymocytes following dexamethazone treatment

hematopoietic system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory