Phenotypes associated with this allele

• Allele Symbol: Idd7^NOD/ShiLt
• Allele Name: NOD/ShiLt
• Allele ID: MGI:3036765
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Idd7^NOD/ShiLt/Idd7^NOD/ShiLt	involves: B10.NOD-H2^g7 * NOD/Lt	MGI:3038160
hm2	Idd7^NOD/ShiLt/Idd7^NOD/ShiLt	involves: C57BL/6 * NOD/ShiLt	MGI:3783684
hm3	Idd7^NOD/ShiLt/Idd7^NOD/ShiLt	involves: NOD/Lt * NON.NOD-H2^g7/LtJ	MGI:3037639

Genotype
MGI:3038160

hm1

• Allelic Composition: Idd7^NOD/ShiLt/Idd7^NOD/ShiLt
• Genetic Background: involves: B10.NOD-H2^g7 * NOD/Lt

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal glucose homeostasis ( J:13557 , J:28947 )

• resistance to type 1 diabetes (J:13557)

• resistance to type 1 diabetes (J:28947)

Genotype
MGI:3783684

hm2

• Allelic Composition: Idd7^NOD/ShiLt/Idd7^NOD/ShiLt
• Genetic Background: involves: C57BL/6 * NOD/ShiLt

hematopoietic system

abnormal T cell clonal deletion ( J:131557 )

• decreased intrathymic deletion of CD4+CD8+ AI4 TCR-expressing T-cells

immune system

abnormal T cell clonal deletion ( J:131557 )

• decreased intrathymic deletion of CD4+CD8+ AI4 TCR-expressing T-cells

Genotype
MGI:3037639

hm3

• Allelic Composition: Idd7^NOD/ShiLt/Idd7^NOD/ShiLt
• Genetic Background: involves: NOD/Lt * NON.NOD-H2^g7/LtJ

homeostasis/metabolism

abnormal glucose homeostasis ( J:28947 )

• resistance to insulin dependent diabetes