Phenotypes associated with this allele

• Allele Symbol: Hdp1^Jrt
• Allele Name: high doppler 1, Janet Rossant
• Allele ID: MGI:3037031
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Hdp1^Jrt/Hdp1^+	involves: C3H/HeJ * C57BL/6J	MGI:3037563

Genotype
MGI:3037563

ht1

• Allelic Composition: Hdp1^Jrt/Hdp1⁺
• Genetic Background: involves: C3H/HeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:88256 )

N • the cardiovascular phenotypes reported were observed in the G1-G4 generations of a C3H/HeJ backcross; penetrance is low so G3 crosses with C57BL/6J and 129S1/SvImJ were used to maintain phenotype.

aortic hypertrophy ( J:88256 )

• aortic hypertrophy noted in pathology findings

abnormal aortic valve morphology ( J:88256 )

• pathology findings include aortic valve endocardiosis

increased heart ventricle size ( J:88256 )

• ventricular hypertrophy noted in pathology findings

dilated heart ventricle ( J:88256 )

• ventricular dilation noted in pathology findings

abnormal blood flow velocity ( J:88256 )

• mice exhibit high ascending aortic peak blood velocity waveforms, stroke distance and mean velocity in vivo; ultrabiomicroscope ultrasound analysis indicates a narrow outflow tract with myocardial hypertrophy