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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ebf3tm1Reed
targeted mutation 1, Randall R Reed
MGI:3037961
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ebf3tm1Reed/Ebf3tm1Reed involves: 129S1/Sv * 129X1/SvJ MGI:3038081
cx2
 		Ebf2tm1Reed/Ebf2+
Ebf3tm1Reed/Ebf3+ 		involves: 129S1/Sv * 129X1/SvJ MGI:3038083


Genotype
MGI:3038081
hm1
Allelic
Composition		 Ebf3tm1Reed/Ebf3tm1Reed
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ebf3tm1Reed mutation (0 available); any Ebf3 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:88585 )
• most mice died within 1 day of birth, with the rest dying by postnatal day 2

nervous system




Genotype
MGI:3038083
cx2
Allelic
Composition		 Ebf2tm1Reed/Ebf2+
Ebf3tm1Reed/Ebf3+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ebf2tm1Reed mutation (0 available); any Ebf2 mutation (30 available)
Ebf3tm1Reed mutation (0 available); any Ebf3 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:88585 )
N
• unlike either Ebf2tm1Reed and Ebf3tm1Reed homozygotes, the olfactory bulb is of normal size and shape
abnormal olfactory neuron innervation pattern ( J:88585 )
• olfactory neurons fail to project to the dorsal olfactory bulb




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory