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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cd93tm1Mbo
targeted mutation 1, Marina Botto
MGI:3038703
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cd93tm1Mbo/Cd93tm1Mbo either: 129/Sv or B6.129-Cd93tm1Mbo or (involves: 129/Sv * C57BL/6) MGI:3038842


Genotype
MGI:3038842
hm1
Allelic
Composition
Cd93tm1Mbo/Cd93tm1Mbo
Genetic
Background
either: 129/Sv or B6.129-Cd93tm1Mbo or (involves: 129/Sv * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd93tm1Mbo mutation (0 available); any Cd93 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• phagocytosis of apoptotic cells by, but not recruitment of, thioglycolate stimulated peritoneal macrophages is impaired in mutants compared to wild-type mice
• phagocytosis of coated red blood cells by thioglycolate stimulated peritoneal macrophages is unaffected
• leukocyte migration is not different in mutants compared to wild-type mice

hematopoietic system
• phagocytosis of apoptotic cells by, but not recruitment of, thioglycolate stimulated peritoneal macrophages is impaired in mutants compared to wild-type mice
• phagocytosis of coated red blood cells by thioglycolate stimulated peritoneal macrophages is unaffected
• leukocyte migration is not different in mutants compared to wild-type mice

cellular
• phagocytosis of apoptotic cells by, but not recruitment of, thioglycolate stimulated peritoneal macrophages is impaired in mutants compared to wild-type mice
• phagocytosis of coated red blood cells by thioglycolate stimulated peritoneal macrophages is unaffected
• leukocyte migration is not different in mutants compared to wild-type mice





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory