limbs/digits/tail
curly tail
(
J:169664
)
• 47% (30 of 64) of adults have a looped or kinky tail
|
kinked tail
(
J:169664
)
• 47% (30 of 64) of adults have a looped or kinky tail
|
nervous system
spina bifida
(
J:169664
)
• in 12% (6 of 50) of embryos in the lumbosacral region
• however, none of the embryos show craniorachischisis
|
reproductive system
|
• present in 78% (21 of 27) of females
|
|
• 32% (12 of 37) of males appear to be infertile
• infertile males are able to set copulatory plugs and do not have any obvious defects in spermatogenesis
|
vision/eye
N |
• unlike Vangl2Lp homozygotes, eyelid closure is normal
|
embryo
spina bifida
(
J:169664
)
• in 12% (6 of 50) of embryos in the lumbosacral region
• however, none of the embryos show craniorachischisis
|