Phenotypes associated with this allele

• Allele Symbol: Cul7^tm1Jdec
• Allele Name: targeted mutation 1, James A DeCaprio
• Allele ID: MGI:3039533
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cul7^tm1Jdec/Cul7^tm1Jdec	involves: C57BL/6 * CD-1	MGI:3039535

Genotype
MGI:3039535

hm1

• Allelic Composition: Cul7^tm1Jdec/Cul7^tm1Jdec
• Genetic Background: involves: C57BL/6 * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:85161 )

• mice die immediately after birth due respiratory distress

cardiovascular system

abnormal vascular development ( J:85161 )

hemorrhage ( J:85161 )

• dermal and hypodermal hemorrhaging is observed in fetuses during late gestation

embryo

decreased embryo size ( J:85161 )

• reduced growth putatively due to placental defects

decreased trophoblast giant cell number ( J:85161 )

abnormal placenta development ( J:85161 )

• impaired trophoblast lineage differentiation

• abnormal vascular structure

growth/size/body

decreased embryo size ( J:85161 )

• reduced growth putatively due to placental defects

respiratory system

respiratory distress ( J:85161 )