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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(HRAS)7Mok
transgene insertion 7, Motoya Katsuki
MGI:3039662
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Krastm1Mok/Krastm1Mok
Tg(HRAS)7Mok/0 		either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361206
cx2
 		Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Krastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)7Mok/0 		either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361207
tg3
 		Tg(HRAS)7Mok/? involves: C57BL/6 MGI:4819239


Genotype
MGI:4361206
cx1
Allelic
Composition		 Krastm1Mok/Krastm1Mok
Tg(HRAS)7Mok/0
Genetic
Background		 either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Tg(HRAS)7Mok mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:135610 )
• mice survive and reproduce
• hearts are normal




Genotype
MGI:4361207
cx2
Allelic
Composition		 Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Krastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)7Mok/0
Genetic
Background		 either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
Tg(HRAS)7Mok mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:135610 )
• born in expected numbers




Genotype
MGI:4819239
tg3
Allelic
Composition		 Tg(HRAS)7Mok/?
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased adenocarcinoma incidence ( J:64968 )
• harderian gland adenocarcinomas
increased sarcoma incidence ( J:64968 )
• 6/9 develop angiosarcomas

respiratory system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory