Phenotypes associated with this allele

• Allele Symbol: Tg(MMTVTGFA)254Rjc
• Allele Name: transgene insertion 254, Robert J Coffey
• Allele ID: MGI:3040319
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(MMTVTGFA)254Rjc/0	involves: C57BL/6 * DBA/2	MGI:3800198

Genotype
MGI:3800198

tg1

• Allelic Composition: Tg(MMTVTGFA)254Rjc/0
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

increased mammary adenocarcinoma incidence ( J:72085 )

mammary gland hyperplasia ( J:72085 )

♀ • female mice develop cystic and solid hyperplasias

enlarged sebaceous gland ( J:72085 )

• mice exhibit sebaceous gland hyperplasia

neoplasm

increased mammary adenocarcinoma incidence ( J:72085 )

behavior/neurological

abnormal nursing ( J:72085 )

♀ • females cannot nurse her young

integument

increased mammary adenocarcinoma incidence ( J:72085 )

mammary gland hyperplasia ( J:72085 )

♀ • female mice develop cystic and solid hyperplasias

enlarged sebaceous gland ( J:72085 )

• mice exhibit sebaceous gland hyperplasia

abnormal skin condition ( J:72085 )

• mice exhibit multiple, raised, white plaques and nodules on the abdominal skin