Phenotypes associated with this allele

• Allele Symbol: Angpt2^{tm2(Angpt1)Gdy}
• Allele Name: targeted mutation 2, George D Yancopoulos
• Allele ID: MGI:3040930
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Angpt2^tm2(Angpt1)Gdy/Angpt2^tm2(Angpt1)Gdy	involves: 129P2/OlaHsd * C57BL/6	MGI:3041968

Genotype
MGI:3041968

hm1

• Allelic Composition: Angpt2^{tm2(Angpt1)Gdy}/Angpt2^{tm2(Angpt1)Gdy}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal angiogenesis ( J:89618 )

• impaired postnatal vascular remodeling in the eye

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:89618 )

N • chylous ascites was not observed

immune system

immune system phenotype ( J:89618 )

N • abnormalities were not observed in the lymphatic system, they were rescued by the expression of the transgenic Agpt