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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rps7Mtu
montu
MGI:3043039
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rps7Mtu/Rps7Mtu involves: BALB/cOlaHsd * C3H/HeH MGI:3057105
ht2
 		Rps7Mtu/Rps7+ (C3H/HeH x BALB/cOlaHsd)F1 MGI:5500162
ht3
 		Rps7Mtu/Rps7+ involves: BALB/cOlaHsd * C3H/HeH MGI:3057104


Genotype
MGI:3057105
hm1
Allelic
Composition		 Rps7Mtu/Rps7Mtu
Genetic
Background		 involves: BALB/cOlaHsd * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rps7Mtu mutation (3 available); any Rps7 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neural crest cell number ( J:93195 )
• decreased numbers of neural crest cells at E9.5.
abnormal hindbrain morphology ( J:93195 )
• open hind brain

embryo
decreased neural crest cell number ( J:93195 )
• decreased numbers of neural crest cells at E9.5.




Genotype
MGI:5500162
ht2
Allelic
Composition		 Rps7Mtu/Rps7+
Genetic
Background		 (C3H/HeH x BALB/cOlaHsd)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rps7Mtu mutation (3 available); any Rps7 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:195156 )
• 72% viability




Genotype
MGI:3057104
ht3
Allelic
Composition		 Rps7Mtu/Rps7+
Genetic
Background		 involves: BALB/cOlaHsd * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rps7Mtu mutation (3 available); any Rps7 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Rps7Mtu/Rps7+ mice exhibiting a white belly spot and kinked tail

mortality/aging
premature death ( J:195156 )
• 26% viability

skeleton
decreased vertebrae number ( J:195156 )
• 52 to 55 versus 55 to 57 in wild-type mice
abnormal vertebral arch morphology ( J:195156 )
• disorganization of vertebral processes and arches in the cervical vertebrae

nervous system
enlarged brain ventricles ( J:195156 )
• in adult mice
thin cerebral cortex ( J:195156 )
• in adult mice

limbs/digits/tail
curly tail ( J:93195 )
• looped tail

pigmentation

behavior/neurological
abnormal spatial working memory ( J:195156 )
• in a spontaneous alternation test

growth/size/body
decreased body size ( J:195156 )

hematopoietic system

integument




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory