Phenotypes associated with this allele

• Allele Symbol: Tg(MMTVTGFA)64Rjc
• Allele Name: transgene insertion 64, Robert J Coffey
• Allele ID: MGI:3043578
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(MMTVTGFA)64Rjc/0	involves: C57BL/6 * DBA/2	MGI:3800200

Genotype
MGI:3800200

tg1

• Allelic Composition: Tg(MMTVTGFA)64Rjc/0
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal mammary gland morphology ( J:28453 , J:72085 )

♀ • at 3 months of age and after only one pregnancy, the female founder mouse developed mammary tissue dysplasia with large, bizarre nuclei, epithelial hyperplasia and stromal proliferation (J:28453)

♀ • female mice develop cystic and solid hyperplasias (J:72085)

♀ • mice exhibit hyperplasia of all components of the mammary gland (J:72085)

increased mammary gland tumor incidence ( J:72085 )

• one mouse developed an adenoma

• however, no adenocarcinomas are observed

behavior/neurological

abnormal nursing ( J:72085 )

♀ • females cannot nurse her young

neoplasm

increased mammary gland tumor incidence ( J:72085 )

• one mouse developed an adenoma

• however, no adenocarcinomas are observed

integument

abnormal mammary gland morphology ( J:28453 , J:72085 )

♀ • at 3 months of age and after only one pregnancy, the female founder mouse developed mammary tissue dysplasia with large, bizarre nuclei, epithelial hyperplasia and stromal proliferation (J:28453)

♀ • female mice develop cystic and solid hyperplasias (J:72085)

♀ • mice exhibit hyperplasia of all components of the mammary gland (J:72085)

increased mammary gland tumor incidence ( J:72085 )

• one mouse developed an adenoma

• however, no adenocarcinomas are observed