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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Epha5tm1Jgf
targeted mutation 1, John G Flanagan
MGI:3043641
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Epha5tm1Jgf/Epha5tm1Jgf Not Specified MGI:3043696


Genotype
MGI:3043696
hm1
Allelic
Composition		 Epha5tm1Jgf/Epha5tm1Jgf
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Epha5tm1Jgf mutation (0 available); any Epha5 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal sensory neuron innervation pattern ( J:90078 )
• retinal axon mapping abnormalities with temporal axons shifted posteriorly and nasal axons anteriorly
• the entire target, the superior colliculus, remained filled with retinal axons
• the shift of axons was not accompanied by increased responsiveness to tectal repellent activity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory