All Phenotypes Hip1<tm2.1Tsr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hip1^tm2.1Tsr
targeted mutation 2.1, Theodora S Ross
MGI:3044188

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hip1^tm2.1Tsr/Hip1^tm2.1Tsr	involves: 129X1/SvJ	MGI:3044675

Allelic Composition	Hip1^tm2.1Tsr/Hip1^tm2.1Tsr
Genetic Background	involves: 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hip1^tm2.1Tsr mutation (0 available); any Hip1 mutation (67 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:90400 )

N	• increased resistance to 5-fluorouracil (5-FU) induced myeloablation relative to wild-type

reproductive system

male infertility ( J:90400 )

skeleton

skeleton phenotype ( J:90400 )

N	• neither osteoporosis or osteoarthritis was observed in mice exhibiting skeletal defects

kyphosis ( J:90400 )

• observed at 4 months of age

vision/eye

vision/eye phenotype ( J:90400 )

N	• mice did not exhibit microphthalmia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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