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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Sigmar1tm1Lmon
targeted mutation 1, Lluis Montoliu
MGI:3044771
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Sigmar1tm1Lmon/Sigmar1tm1Lmon either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1) MGI:3044773


Genotype
MGI:3044773
hm1
Allelic
Composition
Sigmar1tm1Lmon/Sigmar1tm1Lmon
Genetic
Background
either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sigmar1tm1Lmon mutation (2 available); any Sigmar1 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mean mobile time during spontaneous activity is significantly lower for homozygous mutants
• a receptor agonist (SKF-10 047) fails to induce hyperactivity in homozygous mutant mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory