All Phenotypes Ghrl<tm1Mws> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ghrl^tm1Mws
targeted mutation 1, Mark W Sleeman
MGI:3045041

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ghrl^tm1Mws/Ghrl^tm1Mws	involves: C57BL/6	MGI:3045042

Allelic Composition	Ghrl^tm1Mws/Ghrl^tm1Mws
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ghrl^tm1Mws mutation (0 available); any Ghrl mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

abnormal adipose tissue amount ( J:90698 )

• on a high fat diet homozygous mutants tend to have a decrease in percentage body fat and an increase in percentage lean body mass without any significant difference in body weight compared to wild-type mice

homeostasis/metabolism

decreased respiratory quotient ( J:90698 )

• on a high fat diet homozygous mutants have decreased respiratory quotients indicating an increase in utilization of fat as an energy source

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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