All Phenotypes Or8a1<tm2Mom> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Or8a1^tm2Mom
targeted mutation 2, Peter Mombaerts
MGI:3045137

Summary

8 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Or8a1^tm2Mom/Or8a1^tm26Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694129
ht2	Or8a1^tm2Mom/Or8a1^tm9Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694204
ht3	Or8a1^tm2Mom/Or8a1^tm10Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694206
ht4	Or8a1^tm2Mom/Or8a1^{tm11(Or8a1b)Mom}	involves: 129P2/OlaHsd * C57BL/6	MGI:3694131
ht5	Or8a1^tm2Mom/Or8a1^tm4Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694199
ht6	Or8a1^tm2Mom/Or8a1^tm8Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694203
cx7	Or8a1^tm2Mom/Or8a1⁺ Or8a1b^tm6Mom/Or8a1b⁺	involves: 129P2/OlaHsd * C57BL/6	MGI:3694130
cx8	Cnga2^tm1Mom/Cnga2^tm1Mom Or8a1^tm2Mom/Or8a1^tm4Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694207

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm26Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm26Mom mutation (3 available); any Or8a1 mutation (69 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:90716 )

abnormal olfactory neuron innervation pattern ( J:90716 )

• atypical glomeruli are formed in which some co-mingling of Olfr151^tm2Momaxons with both Olfr151 and Olfr160 axons occurs, but Olfr151^tm2Momaxons are shared between glomeruli

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm9Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm9Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb I axons segregate from Hyb B axons

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm10Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm10Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb F axons co-converge with but segregate from Hyb B axons

Allelic Composition	Or8a1^tm2Mom/Or8a1^{tm11(Or8a1b)Mom}
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^{tm11(Or8a1b)Mom} mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:90716 )

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb B axons co-converge to a large extent and co-mingle with Olfr151^{tm11(Olfr160)Mom} axons

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm4Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm4Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• axons co-converge without co-mingling, and segregate into separate compartments within the same glomeruli

• after naris occlusion before glomerular formation, axons still segregate into separate compartments within the same glomeruli, but there are supernumerary glomeruli

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm8Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm8Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb H axons segregate from Hyb B axons

Allelic Composition	Or8a1^tm2Mom/Or8a1⁺ Or8a1b^tm6Mom/Or8a1b⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1b^tm6Mom mutation (4 available); any Or8a1b mutation (35 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:90716 )

abnormal olfactory neuron innervation pattern ( J:90716 )

• Olfr151 and Olfr160 axons only intermingle to a small extent; atypical glomeruli are formed in which some co-mingling of Olfr151^tm2Momaxons with both Olfr151 and Olfr160 axons occurs, but Olfr151^tm2Momaxons are shared between glomeruli

Allelic Composition	Cnga2^tm1Mom/Cnga2^tm1Mom Or8a1^tm2Mom/Or8a1^tm4Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cnga2^tm1Mom mutation (2 available); any Cnga2 mutation (17 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm4Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb B and Hyb D axons segregate into separate into separate compartments within the same glomeruli

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24