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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Or8a1tm4Mom
targeted mutation 4, Peter Mombaerts
MGI:3045139
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Or8a1tm4Mom/Or8a1tm25Mom involves: 129P2/OlaHsd * C57BL/6 MGI:3694193
ht2
 		Or8a1tm2Mom/Or8a1tm4Mom involves: 129P2/OlaHsd * C57BL/6 MGI:3694199
ht3
 		Or8a1tm1Mom/Or8a1tm4Mom involves: 129P2/OlaHsd * C57BL/6 MGI:3694200
cx4
 		Cnga2tm1Mom/Cnga2tm1Mom
Or8a1tm2Mom/Or8a1tm4Mom 		involves: 129P2/OlaHsd * C57BL/6 MGI:3694207


Genotype
MGI:3694193
ht1
Allelic
Composition		 Or8a1tm4Mom/Or8a1tm25Mom
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1tm25Mom mutation (6 available); any Or8a1 mutation (69 available)
Or8a1tm4Mom mutation (1 available); any Or8a1 mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory neuron innervation pattern ( J:90716 )
• Hyb D axons co-converge and co-mingle with Olfrtm25Mom axons




Genotype
MGI:3694199
ht2
Allelic
Composition		 Or8a1tm2Mom/Or8a1tm4Mom
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1tm4Mom mutation (1 available); any Or8a1 mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory neuron innervation pattern ( J:90716 )
• axons co-converge without co-mingling, and segregate into separate compartments within the same glomeruli
• after naris occlusion before glomerular formation, axons still segregate into separate compartments within the same glomeruli, but there are supernumerary glomeruli




Genotype
MGI:3694200
ht3
Allelic
Composition		 Or8a1tm1Mom/Or8a1tm4Mom
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1tm1Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1tm4Mom mutation (1 available); any Or8a1 mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory neuron innervation pattern ( J:90716 )
• axons co-converge with partial segregation in glomeruli




Genotype
MGI:3694207
cx4
Allelic
Composition		 Cnga2tm1Mom/Cnga2tm1Mom
Or8a1tm2Mom/Or8a1tm4Mom
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cnga2tm1Mom mutation (2 available); any Cnga2 mutation (17 available)
Or8a1tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1tm4Mom mutation (1 available); any Or8a1 mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory neuron innervation pattern ( J:90716 )
• Hyb B and Hyb D axons segregate into separate into separate compartments within the same glomeruli




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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory