All Phenotypes Or8a1<tm4Mom> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Or8a1^tm4Mom
targeted mutation 4, Peter Mombaerts
MGI:3045139

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Or8a1^tm4Mom/Or8a1^tm25Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694193
ht2	Or8a1^tm2Mom/Or8a1^tm4Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694199
ht3	Or8a1^tm1Mom/Or8a1^tm4Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694200
cx4	Cnga2^tm1Mom/Cnga2^tm1Mom Or8a1^tm2Mom/Or8a1^tm4Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3694207

Allelic Composition	Or8a1^tm4Mom/Or8a1^tm25Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm25Mom mutation (6 available); any Or8a1 mutation (69 available)
Or8a1^tm4Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:90716 )

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb D axons co-converge and co-mingle with Olfr^tm25Mom axons

Allelic Composition	Or8a1^tm2Mom/Or8a1^tm4Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm4Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• axons co-converge without co-mingling, and segregate into separate compartments within the same glomeruli

• after naris occlusion before glomerular formation, axons still segregate into separate compartments within the same glomeruli, but there are supernumerary glomeruli

Allelic Composition	Or8a1^tm1Mom/Or8a1^tm4Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1^tm1Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm4Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• axons co-converge with partial segregation in glomeruli

Allelic Composition	Cnga2^tm1Mom/Cnga2^tm1Mom Or8a1^tm2Mom/Or8a1^tm4Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cnga2^tm1Mom mutation (2 available); any Cnga2 mutation (17 available)
Or8a1^tm2Mom mutation (1 available); any Or8a1 mutation (69 available)
Or8a1^tm4Mom mutation (1 available); any Or8a1 mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory neuron innervation pattern ( J:90716 )

• Hyb B and Hyb D axons segregate into separate into separate compartments within the same glomeruli

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