Phenotypes associated with this allele

• Allele Symbol: Rho^{tm3(RHO/GFP)Jhw}
• Allele Name: targeted mutation 3, John H Wilson
• Allele ID: MGI:3046187
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rho^tm3(RHO/GFP)Jhw/Rho^tm3(RHO/GFP)Jhw	either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * C57BL/6-Tyr^c)	MGI:3046198
ht2	Rho^tm3(RHO/GFP)Jhw/Rho^+	either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * C57BL/6-Tyr^c)	MGI:3046199

Genotype
MGI:3046198

hm1

• Allelic Composition: Rho^{tm3(RHO/GFP)Jhw}/Rho^{tm3(RHO/GFP)Jhw}
• Genetic Background: either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * C57BL/6-Tyr^c)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

retina degeneration ( J:91038 )

• retinas begin to degenerate within 3-5 months after birth

• retinal degeneration is more severe than in Rho^tm2Jhw homozygotes

Genotype
MGI:3046199

ht2

• Allelic Composition: Rho^{tm3(RHO/GFP)Jhw}/Rho⁺
• Genetic Background: either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * C57BL/6-Tyr^c)

vision/eye

retina degeneration ( J:91038 )

• mild retinal degeneration is seen with the number of nuclei in the outer nuclear layer being reduced to about 80% wild-type