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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fggtm2Jld
targeted mutation 2, Jay L Degen
MGI:3046446
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fggtm2Jld/Fggtm2Jld involves: 129P2/OlaHsd * Black Swiss * C57BL/6 MGI:3046447


Genotype
MGI:3046447
hm1
Allelic
Composition		 Fggtm2Jld/Fggtm2Jld
Genetic
Background		 involves: 129P2/OlaHsd * Black Swiss * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fggtm2Jld mutation (0 available); any Fgg mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:90908 )
N
• blood coagulation was normal
• platelet numbers were normal
abnormal neutrophil physiology ( J:90908 )
• neutrophil adhesion to fibrinogen failed

immune system
abnormal neutrophil physiology ( J:90908 )
• neutrophil adhesion to fibrinogen failed
increased susceptibility to bacterial infection ( J:90908 )
• defective bacterial clearance of S. aureus after peritoneal infection




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory